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4-Chloropyrrolo[2,3-d]pyrimidine

4-Chloropyrrolo[2,3-d]pyrimidine
API Intermediate CAS: 3680-69-1

4-Chloropyrrolo[2,3-d]pyrimidine

4-Chloropyrrolo[2,3-d]pyrimidine (CAS No. 3680-69-1) is a high-purity fused heterocyclic compound widely used as an important pharmaceutical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and biologically active molecules. The reactive chlorine atom at the 4-position enables efficient nucleophilic substitution reactions, making this compound a valuable building block for the preparation of kinase inhibitors, nucleoside analogues, antiviral agents, and oncology drug candidates. It is extensively employed in medicinal chemistry, pharmaceutical process development, and custom synthesis projects. Hestur Pharma, Hyderabad, India, manufactures and supplies premium-quality 4-Chloropyrrolo[2,3-d]pyrimidine with consistent purity and excellent batch-to-batch quality for pharmaceutical companies, CROs, CDMOs, research organizations, and specialty chemical manufacturers. Our product is suitable for laboratory research, pilot-scale production, and commercial manufacturing. We offer flexible packaging, competitive pricing, comprehensive documentation including Certificate of Analysis (COA) and Safety Data Sheet (SDS), and dependable domestic and international supply. Hestur Pharma is committed to delivering high-quality pharmaceutical intermediates and custom synthesis solutions that meet global industry standards.

Pack Size Stock Price (₹) Quantity Delivery Time Action
5g 10
₹2,126 ₹2,126
1
5–7 Business Days
25g 10
₹3,560 ₹3,560
1
5–7 Business Days
100g 10
₹5,896 ₹5,896
1
5–7 Business Days
250g 5
₹10,750 ₹10,750
1
5–7 Business Days

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Category API Intermediate
Chemical Name 4-Chloropyrrolo[2,3-d]pyrimidine
CAS No. 3680-69-1
Synonyms 4-Chloropyrrolo[2,3-d]pyrimidine, 4-Chloro-7-deazapurine, 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Chemical Formula C₆H₄ClN₃
Molecular Weight 153.57 g/mol g/mol
Applications 4-Chloropyrrolo[2,3-d]pyrimidine (CAS No. 3680-69-1) is a versatile pharmaceutical intermediate widely used in the synthesis of kinase inhibitor APIs. It is a key building block for drugs such as Tofacitinib, Ruxolitinib, Baricitinib, Capivasertib, Pacritinib, Peficitinib, Oclacitinib, Vibegron, Ivarmacitinib, Itacitinib, Tinengotinib, Abrocitinib, Delgocitinib, and Ritlecitinib. It is extensively used in the development of treatments for cancer, autoimmune, inflammatory, and dermatological diseases.
Test Specification
Appearance White to Off-White Crystalline Powder
Purity by HPLC ≥98.0%

Usage

4-Chloropyrrolo[2,3-d]pyrimidine is widely used as a pharmaceutical intermediate in the synthesis of kinase inhibitors, nucleoside analogues, antiviral compounds, and other heterocyclic APIs. It is suitable for medicinal chemistry, API development, custom synthesis, CRO services, CDMO manufacturing, and research laboratories.

Safety

Handle using appropriate personal protective equipment (PPE), including gloves, safety goggles, and protective clothing. Avoid inhalation of dust and contact with skin or eyes. Use in a well-ventilated laboratory or fume hood. Store in a tightly sealed container in a cool, dry place away from moisture and incompatible substances. Refer to the latest Safety Data Sheet (SDS) before handling.

Other Information

-Grade: Research Grade / Industrial Grade
-Purity: ≥99%
-Packaging: 25 g, 100 g, 500 g, 1 kg, 5 kg, 25 kg
-COA available on request
-SDS available on request
-Custom packaging available
-Bulk quantities available
-Suitable for laboratory, pilot-scale, and commercial manufacturing
-Worldwide shipping available

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